polycystic ovary syndrome
Conditions
Interventions
Experimental group:taking metformin
Experimental group:Taking Qinlian Duonang granules
control group:taking metformin
control group:Taking the Simulant Qinlian Duonang granules
Sponsors
Guanganmen Hospital, China Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 35 Years
Inclusion criteria
Inclusion criteria: 1. Fully understand, know and voluntarily participate in this study and sign the informed consent form; 2. It meets the diagnostic criteria of polycystic ovary syndrome (PCOS) in western medicine; 3. Meet the diagnostic criteria of insulin resistance (IR); 4. Conforming to the syndrome differentiation standard of stomach heat and spleen deficiency in traditional Chinese medicine; 5. 18 = age = 35 years.
Exclusion criteria
Exclusion criteria: 1. Menarche less than 2 years; 2. Patients with other endocrine diseases such as thyroid, adrenal diseases and diabetes; 3. Patients with severe diseases such as cardio-cerebrovascular, liver, kidney and hematopoietic system and thrombotic diseases, and those with serum alanine aminotransferase (ALT), aspartate aminotransferase (AST) or serum creatinine (CREA) greater than 2 times the upper limit of normal reference value. 4. Patients with peptic ulcer or malabsorption syndrome; 5. Patients with mental illness or cancer; 6. Those who have taken hormone drugs (except progesterone), metformin, or traditional Chinese medicine decoction within the past three months, or have accepted other clinical research; 7. Those who are allergic to the ingredients of traditional Chinese medicine, and those with allergic constitution; 8. Alcoholics and/or psychoactive substances, drug abusers and addicts; 9. Pregnancy planners in the last 3 months; 10. Subjects with poor compliance or unable to follow up regularly.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Biphasic rate of basal body temperature;Insulin related indexes; | — |
Secondary
| Measure | Time frame |
|---|---|
| Female reproductive hormone;TCM symptom score;Menstruation rate;Related indexes of glucose metabolism;Acanthosis nigricans score;Lipid metabolism level;Anthropometry;Acne score;Quality of life scale for patients with PCOS;SCL-90 scale;Patient self-evaluation; | — |
Countries
China
Contacts
Public ContactXinmin Liu
Guanganmen Hospital, China Academy of Chinese Medical Sciences
Outcome results
None listed