Study on accurate diagnosis and treatment of lower reproductibe tract infection in Chinese female population

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2200058912

Enrollment

Unknown

Registered

2022-04-19

Start date

2022-06-01

Completion date

Unknown

Last updated

2024-01-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lower reproductive tract infection

Interventions

Case group:NA

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Inclusion criteria for healthy people: 1. The chief complaint and physical examination showed no abnormal symptoms; 2. Age 16-45; 3. Have a history of sexual life; 4. Regular menstruation; 5. Not pregnant; 6. There was no use of antibiotics and hormones in the past month; 7. No basic disease; 8. No long-term medication history; 9. No STIs. Inclusion criteria for bacterial vaginosis and aerobic vaginitis: 1. Symptoms in chief complaint and physical examination; 2. Morphological abnormality of gram staining (Nugent score = 4 points or Donders' score = 3 points); 3. Age 16-45; 4. Have a history of sexual life; 5. Regular menstruation; 6. Not pregnant; 7. There was no use of antibiotics and hormones in the past month; 8. No STIs.

Exclusion criteria

Exclusion criteria: 1. People with other or combined with other reproductive tract infections, such as trichomonal vaginitis (TV), vulvovaginal candidiasis (VVC), and sexually transmitted diseases; 2. Patients with gynecological malignancies, such as cervical cancer, endometrial cancer, ovarian cancer, etc; 3. Pregnant and lactating women; 4. Patients with serious primary diseases such as heart, brain, liver, kidney, blood and endocrine system; 5. Those who were treated with systemic or local antibiotics four weeks before enrollment; 6. Patients with other diseases requiring long-term treatment with hormones and immunosuppressants; 7. Those with mental and neurological diseases who cannot cooperate, and those with alcohol and drug abuse history.

Design outcomes

Primary

Measure	Time frame
microbial a diversity;microbial ß diversity;	—

Countries

China

Contacts

Public ContactLan Zhu

Peking Union Medical College Hospital,Chinese Academy of Medical Sciences & Peking Union Medical College

zhu_julie@vip.sina.com+86 10 69155016

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026