Effects of remazolam combined with low-dose propofol on hemodynamics during induction of general anesthesia in patients with hypertension

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200058911

Enrollment

Unknown

Registered

2022-04-19

Start date

2022-04-18

Completion date

Unknown

Last updated

2024-01-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hypertension

Interventions

Propofol Group:Propofol

Propofol+Remazolam Group:Propofol+Remazolam

Eligibility

Sex/Gender

All

Age

30 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Surgical treatment in our hospital; 2. Comply with the relevant diagnostic criteria of essential hypertension in the Chinese Guidelines for the Prevention and Treatment of Hypertension (2021 Edition); 3. ASA is classified as Grade I-II; 4. Hypertension is classified into 1-2 grades; 5. The general health is good and the blood pressure control is ideal (120 140/65 85 mmHg); 6. No endocrine disease; 7. Age< 80 years; 8. Good compliance and normal communication.

Exclusion criteria

Exclusion criteria: 1. Complicated with arrhythmia, sinus bradycardia and other heart diseases and pulmonary dysfunction; 2. Secondary hypertension; Complicated with severe organic diseases such as liver and kidney; 3. Abnormal coagulation and immune function; 4. Complicated with malignant tumor; 5. Take antidepressants and sedatives for a long time.

Design outcomes

Primary

Measure	Time frame
Hemodynamic changes during induction;	—

Countries

China

Contacts

Public ContactZhong Yu

First Affiliated Hospital of Guangxi Medical University

zzlugl@163.com+86 15177929679

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026