Coronavirus Diseases (COVID-19)
Conditions
Interventions
Control group:providing basic treatment in accordance with the guidelines for the diagnosis and treatment of New Coronavirus pneumonia (trial version ninth)
Experimental group:Carrying out oral and nasal irrigation four times a day with the solution provided by the study team, and basic treatment in accordance with the guidelines for the diagnosis and tre
Sponsors
Ruijin Hospital,Shanghai Jiaotong University school of medicine
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1.Positive result of COVID-19 infection less than 3 days by RT-PCR; 2.Age between 18-59 years; 3.Asymptomatic infection was diagnosed and medical observation was carried out at the centralized isolation treatment point; 4.can understand and provide informed consent; 5.Commit to follow the research procedures and cooperate in the implementation of the whole process research; 6.Able to communicate with the study team by phone, email or text.
Exclusion criteria
Exclusion criteria: 1.Patients with a history of nasal surgery, chronic sinusitis, or routine daily nasal flushing or nasal drug intervention; 2.Patients with thyroid diseases, respiratory diseases or other serious basic diseases; 3.Allergy to iodine; 4.Participation in another prospective COVID related research project(clinical trial) within 1 month; 5.Pregnant or breastfeeding women; 6.Pregnancy tests in serum or urine of women of childbearing age were positive; 7.Immunodeficiency patients (such as malignant tumor patients, organ or bone marrow transplant recipients, AIDS patients, and immunosuppressive drugs within 3 months); 8.Other patients considered unsuitable by the investigator to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Viral Negative rate by PCR on the tenth day; | — |
Secondary
| Measure | Time frame |
|---|---|
| the days that viral convert negative;Changes of viral load in pharyngeal swab;clinical discomfort reported by patients: headache, cough, runny nose, chest pain, fever, muscle soreness / fatigue, diarrhea / nausea / vomiting, loss of taste / smell and other symptoms.; | — |
Countries
China
Contacts
Public ContactWu Beiwen
Ruijin Hospital,Shanghai Jiaotong University school of medicine
Outcome results
None listed