Study on placenta-gut-pulmonary axis microecology and lung injury in premature infants based on TLR4/MyD88/NF-?B signaling pathway

Status

Active, not recruiting

Phases

Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2200058862

Enrollment

Unknown

Registered

2022-04-18

Start date

2022-04-18

Completion date

Unknown

Last updated

2024-01-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung injury

Interventions

Upper machine group:no

normal group:no

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Research team: 1. Preterm infants (gestational age<37 weeks) admitted to our obstetrics department and neonatal department from April 1, 2022 to December 30, 2022. It is divided into upper breathing unit and non upper breathing unit. Control group: 1. Term neonates admitted to our obstetrics department and neonatal department from April 1, 2022 to December 30, 2022.

Exclusion criteria

Exclusion criteria: 1. Congenital malformations (including complex congenital heart disease and pulmonary malformations); 2. Genetic metabolic diseases; 3. Chromosome disease; 4. Family members do not agree to participate in the study.

Design outcomes

Primary

Measure	Time frame
tool;	—

Countries

China

Contacts

Public ContactLei Zhang

Chengdu Women's and Children's Central Hospital

534167313@qq.com+86 28 61866049

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026