Allergic rhinitis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. It conforms to the diagnostic criteria in the Diagnosis and Guidelines for Allergic rhinitis formulated by the Nasal Science Group of Otolaryngology Head and Neck Surgery Branch of Chinese Medical Association in 2016; 2. Criteria for drug-resistant allergic rhinitis: patients whose symptoms cannot be controlled after 4 weeks of nasal spray hormone combined with antihistamine treatment; 3. Can tolerate sphenopalatine ganglion pulse radiofrequency therapy; 4. ASA I - II level; 5. 18-60 years old; 6. The patient signed the informed consent in person.
Exclusion criteria
Exclusion criteria: 1. Pregnant or breast-feeding women, menstruating women, and women planning to become pregnant within 3 months; 2. Patients who received other treatments or oral or topical glucocorticoids, antihistamines and immunotherapy within 4 weeks prior to treatment; 3. Congenital nasal malformation, sinus disease, severe nasal septum deviation and nasal polyp; 4. Complicated with specific dermatitis and other refractory diseases or with a history of parasitic infection; 5. Patients complicated with serious cardiovascular and cerebrovascular diseases, patients with liver and renal blood system or malignant tumors, psychiatric patients, diabetes patients, and patients with bleeding tendency; 6. Patients with pacemakers, defibrillators, artificial joints, contraceptive rings, etc. Since MRI is performed in a narrow barrel environment, claustrophobic subjects should not participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rhinitis symptom improvement score;Rhinoconjunctivitis quality of life questionnaire, RQLQ;Functional magnetic resonance examination;Serological indicators; | — |
Countries
China
Contacts
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology