Endometriosis
Conditions
Interventions
Observation group:Etopregnene subcutaneous implant
Control group:Mirena
Sponsors
Jiaxing Maternal and Child Health Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 55 Years
Inclusion criteria
Inclusion criteria: 1. Postoperative patients with endometriosis confirmed by laparoscopic surgery; 2. The visual analogue scale (VAS) of endometriosis with dysmenorrhea before operation >0; 3. Women aged 18-55 (premenopausal) who currently have no fertility requirements and require contraception; 4. Voluntary subjects and signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Severe anemia; 2. Undiagnosed abnormal vaginal bleeding or endometrial lesions; 3. Genital malformations such as mediastinal uterus, double uterus, etc. Uterine cavity 9.5cm; 4. Hormone dependent benign gynecological diseases such as adenomyosis and hysteromyoma; 5. Patients with severe heart, liver and kidney diseases and adrenocortical insufficiency; 6. Combined with malignant tumors (including reproductive system and other systems); The laboratory test value indicates that it has abnormal clinical significance; 7. Allergic constitution or previous allergy to multiple drugs, or allergic to active ingredients or any excipients in the study drug; 8. Suffering from any disease or symptom that may cause the study drug to change absorption, excessive accumulation, affect metabolism or change the mode of excretion; 9. Suffering from clinically significant depression in the current or recent year; 10. Taking analgesics regularly due to other basic diseases; 11. Patients who have participated in other clinical trials within 3 months before screening or who are considered unsuitable by other researchers to participate in this study; 12. The laboratory test value indicates that it has abnormal clinical significance.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS score for dysmenorrhea; | — |
Secondary
| Measure | Time frame |
|---|---|
| Recurrence rate of endometrioid cyst of ovary (%);PBAC;Sugar antigen CA125; | — |
Countries
China
Contacts
Public ContactXiaoji Cai
Jiaxing Maternal and Child Health Hospital
Outcome results
None listed