Obesity
Conditions
Interventions
VCV:Sets the tidal volume based on the ideal weight
VCV-IRV:Sets the tidal volume based on the target tidal volume
PCV:Set the suction pressure according to the target tidal volume
PC-IRV:Set the suction pressure according to the target tidal volume
Sponsors
The Affiliated Hospital of Xuzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Age >= 18 years old, = 40 kg/m2 or BMI >= 35 kg/m2 and undergo laparoscopic gastric volume reduction surgery with metabolic syndromes such as type 2 diabetes, hypertension, and hyperlipidemia.
Exclusion criteria
Exclusion criteria: 1. Patients who cannot tolerate general anesthesia, such as allergies to general anesthesia; 2. Decompensated heart disease (heart failure, myocardial infarction, severe arrhythmias); 3. Severe respiratory diseases (severe obstructive or restrictive lung disease, respiratory failure); 4. Thoracic deformity, lung surgery history and recent respiratory infectious diseases; 5. Severe liver dysfunction (serum total bilirubin >= 2mg/dl); 6. Severe renal dysfunction (glomerular filtration rate<60ml/(min·1.73m2)-1; 7. There are abnormalities in the chest x-ray before surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Dynamic compliance (Cdyn); | — |
Secondary
| Measure | Time frame |
|---|---|
| Plateau pressure (Pplat);Mean pressure (Pmean);Peak pressure (Ppeak);Ratio of physiologic dead space to tidal volume (VD/VT);Hemodynamic parameters;Arterial blood gas analysis;Static compliance (Cst) ;Lung complications;The quality was recovered after surgery; | — |
Countries
China
Contacts
Public ContactWang Guanglei
The Affiliated Hospital of Xuzhou Medical University
Outcome results
None listed