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Construction of a molecular regulatory network for sepsis in children and screening and validation of key immune genes

Construction of a molecular regulatory network for sepsis in children and screening and validation of key immune genes

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200058814
Enrollment
Unknown
Registered
2022-04-17
Start date
2022-04-25
Completion date
Unknown
Last updated
2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sepsis in children

Interventions

Sepsis:None
Healthy controls:None

Sponsors

The Seventh Affiliated Hospital of Sun Yat-Sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 18 Years

Inclusion criteria

Inclusion criteria: 1. Met the diagnostic criteria of sepsis in children, referring to the expert consensus on the diagnosis and treatment of septic shock (septic shock) in children (2015 Edition); 2. The age ranged from 28 days to 18 years.

Exclusion criteria

Exclusion criteria: 1. Those with comorbid malignancies or autoimmune diseases; 2. Organ transplant patients or those using hormones, cytotoxic drugs, or immunosuppressive agents for nearly 2 weeks; 3. Hospital stay was less than 24 hours.

Design outcomes

Primary

MeasureTime frame
ITK;FYN;ATM;FBL;WDR75;FOXO1;—

Countries

China

Contacts

Public ContactChun Chen

The Seventh Affiliated Hospital of Sun Yat-Sen University

chenchun69@126.com+86 13719003063

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026