Diabetic keratopathy
Conditions
Interventions
Control group:None
Sponsors
Qingdao Eye Hospital of Shandong First Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1. Clinical diagnosis of type 2 diabetes; 2. PDR requires vitrectomy; 3. Age> 18 years old; 4. Corneal transparency; 5. Confocal microscopy decreased corneal nerve density; 6. With or without decreased corneal sensitivity.
Exclusion criteria
Exclusion criteria: 1. Combined corneal disease (ulcer, infection, matrix scar or corneal transplantation, etc.); 2. Combined glaucoma and poor intraocular pressure control; 3. Long-term wear of corneal contact lens; 4. History of corneal refractive surgery; 5. Long-term use of eye drops or eye ointment; 6. Autoimmune disease (such as Sjogren's syndrome, rheumatoid arthritis, ankylosing spondylitis, etc.)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Slit-lamp;Sodium fluorescein staining;Corneal sensitivity;Corneal nerve length; | — |
Secondary
| Measure | Time frame |
|---|---|
| RT-OCT (Optical Coherence Tomography);HbA1C;Shirmer test I;Layer gland score;OSDI (Ocular Surface Disease Index);Corneal endothelia count;BUT (Tear Film Break Up Time); | — |
Countries
China
Contacts
Public ContactYangyang Zhang
Qingdao Eye Hospital of Shandong First Medical University
Outcome results
None listed