Asymptomatic patients infected with a novel coronavirus Omicron variant
Conditions
Interventions
Experimental group:Add topical spraying of human interferon a2b solution in the nose and oropharynx to the basic and herbal treatment
Control group:Centralized isolation management, bed rest, application of traditional Chinese medicine, strengthening supportive treatment, ensuring adequate energy and nutrition intake
paying attention to water and electrolyte balance, maintaining a stable internal environment, and closely monitoring vital signs and clinical symptoms.
Sponsors
The First Affiliated Hospital of Anhui Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Age 18-60 years old, male or female; 2. With epidemiological history; 3. Clinically diagnosed as a confirmed case of novel coronavirus infection, the diagnostic criteria are in accordance with the Diagnosis and Treatment Protocol for Novel Coronavirus Pneumonia (Trial ninth Edition); including: (1) The novel coronavirus nucleic acid test is positive; (2) No clinical symptoms; (3) There is no evidence of pneumonia in imaging; 4. No other antiviral drugs and immunomodulatory preparations were used within one week before the diagnosis.
Exclusion criteria
Exclusion criteria: 1. Those who are known to be allergic to interferon; 2. Lupus erythematosus, psoriasis and other autoimmune diseases or immunodeficiency diseases; 3. People with chronic underlying diseases at risk of developing into severe patients, late pregnancy and perinatal women, etc.; 4. Those with epilepsy or other central nervous system dysfunction; 5. Mixed infections with bacteria and other pathogens in the respiratory tract were determined before enrollment; 6. Those who refuse to sign the informed consent form.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Virus negative conversion time; | — |
Secondary
| Measure | Time frame |
|---|---|
| Virus negative conversion rate;Pneumonia confirmation rate; | — |
Countries
China
Contacts
Public ContactYufeng Gao
The First Affiliated Hospital of Anhui Medical University
Outcome results
None listed