Non-small cell lung cancer
Conditions
Interventions
Sponsors
Cancer Hospital Chinese Academy of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Cytological or histological diagnosis of non-small cell lung cancer; 2. Resectable IIIA non-small cell lung cancer (IASLC/UICC staging eighth edition); 3. No previous history of malignant tumors and other malignant tumors at the same time, without any anti-tumor treatment; 4. ECOG score 0-1, heart, lung, liver, brain and kidney function can tolerate surgery; 5. At least one measurable lesion (RECIST v1.1); 6. Age >= 18 years old and <= 75 years old; 7. Sign the written informed consent, and be able to abide by the visits and related procedures stipulated in the program.
Exclusion criteria
Exclusion criteria: 1. Patients with positive driver genes; 2. Immunosuppressive drugs have been used within 3 weeks before the first dose of treatment (excluding prednisone or other glucocorticoids with no more than 10 mg/day of equivalent dose); 3. Known or suspected active autoimmune disease; 4. Known allogeneic organ transplantation (except corneal transplantation) or allogeneic hematopoietic stem cell transplantation; 5. Allergic to any component of monoclonal antibody; 6. Currently suffering from interstitial lung disease; 7. Suffering from other uncontrolled serious diseases; 8. Other acute or chronic diseases that may interfere with the test results of the research.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Major pathological response; | — |
Secondary
| Measure | Time frame |
|---|---|
| pCR (pathological complete response);ORR (objective reponse rate);DFS (disease free survival);OS (overall survival); | — |
Countries
China
Contacts
Public ContactMao Yousheng
Cancer Hospital Chinese Academy of Medical Sciences
Outcome results
None listed