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Establishment and clinical application of risk classification model based on molecular typing of medulloblastoma in children

Establishment and clinical application of risk classification model based on molecular typing of medulloblastoma in children

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200058760
Enrollment
Unknown
Registered
2022-04-16
Start date
2022-05-01
Completion date
Unknown
Last updated
2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

medulloblastoma

Interventions

None listed

Sponsors

Beijing Tiantan Hospital, China Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
0.5 Years to 18 Years

Inclusion criteria

Inclusion criteria: 1. Age 0.5-18 years old (except newborns); 2. Pathologically confirmed medulloblastoma; 3. Have not received other relevant treatment before the operation; 4. Complete head and spinal cord enhanced MRI examination; 5. Tumor samples can be obtained and molecular typing can be determined; 6. Postoperative KPS score >= 70 points; 7. Voluntarily enrolled in the group and able to accept long-term follow-up; 8. Patients or their family members voluntarily sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients who have recently received other drugs or radiation therapy; 2. Patients suffering from acute or chronic infectious diseases or infectious diseases; 3. Patients suffering from uncontrollable neurological, mental diseases or mental disorders, and poor compliance; 4. Patients who cannot receive enhanced MRI scans; 5. Other conditions that the investigator believes that the patient is not suitable for participating in this trial.

Design outcomes

Primary

MeasureTime frame
Age at diagnosis;Sex;Molecular typing;Overall survival;Progression free survival;Quality of life scale;Imaging examinations;Adjunctive treatment(Radiotherapy and chemotherapy)information;

Secondary

MeasureTime frame
Height;weight;

Countries

China

Contacts

Public ContactYongji Tian

Beijing Tiantan Hospital, China Capital Medical University

tianyongji@bjtth.org+86 15801593549

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026