Thyroid carcinoma
Conditions
Interventions
Index test:Imprinted gene mutation or not
Sponsors
Shanghai Tenth People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. At least 18 years old with no gender limitation; 2. Thyroid nodules in line with FNA indications of ATA guidelines; 3. Have not received partial or total thyroidectomy; 4. Cytopathology of Bethesda III-V (especially Bethesda III and IV); 5. Have surgical indications and accept surgery (suspected follicular tumors especially larger ones, try to operate as far as possible); 6. The patients are willing to sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with FNA samples RNA degradation or insufficient epithelial cells; 2. FNA cytopathology was undiagnosed (Bethesda I), clearly benign (Bethesda II) or clearly malignant (Bethesda VI); 3. Postoperative histopathology could not clearly diagnose benign and malignant tumors, or clearly diagnose metastases of other cancers; 4. Incomplete clinical information (Note: Follow-up is available for patients who have no indication for surgery and have not received surgery).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| imprinted gene;sensitivity;specifity;accuracy;area under the receiver operating characteristic curve; | — |
Countries
China
Contacts
Public ContactYifeng Zhang
Shanghai Tenth People's Hospital
Outcome results
None listed