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Clinical observation of Xuefu Zhuyu decoction in the prevention and treatment of radiation induced esophagitis

Clinical observation of Xuefu Zhuyu decoction in the prevention and treatment of radiation induced esophagitis

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200058733
Enrollment
Unknown
Registered
2022-04-15
Start date
2022-05-01
Completion date
Unknown
Last updated
2024-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Esophagus Cancer

Interventions

experimental group:Xuefu zhuyu Decoction combined with standard radiotherapy

Sponsors

Jiangsu Provincial Hospital of TCM
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1. The patient has a definite pathological and cytological diagnosis; 2. Peripheral white blood cells >= 4.0 x 10^9 / L, hemoglobin >= 90g / L, platelets >= 80 x 10^9 / L before radiotherapy; 3. KPS score >= 70 points, expected survival time> 6 months; 4. Liquid diet; 5. No esophageal perforation or active bleeding; 6. No serious heart, lung, liver and kidney function, coagulation dysfunction; 7. Cases in the experimental group still need to meet the Chinese medicine xueyu poison.

Exclusion criteria

Exclusion criteria: 1. Patients with mental illness or intellectual disability; 2. Poor compliance; 3. Allergic to experimental drugs; 4. At the same time participating in other clinical trials; 5. Combining other serious diseases, such as other tumors or serious infections.

Design outcomes

Primary

MeasureTime frame
Blood clotting function;OS, PFS, RFS and TTP;CR, PR, SD, PD;

Countries

China

Contacts

Public ContactYu Dahai

Nanjing University of Chinese Medicine

yudahaipumc@hotmail.com+86 13913982677

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026