Anesthesiology
Conditions
Interventions
RR:remimazolam tosilate-remifentanil
DR:dexmedetomidine- remifentanil
Sponsors
Liaocheng People's Hospital
Eligibility
Sex/Gender
All
Age
45 Years to 65 Years
Inclusion criteria
Inclusion criteria: outpatients undergoing FB with moderate sedation; aged 45 to 65 years; American Society of Anesthesiologists (ASA) ?-?; procedure time is no longer than 30 min; oxygen saturation (SpO2) > 90% in room air
Exclusion criteria
Exclusion criteria: history of known allergy to local anesthetics, RF, Dex, midazolam, propofol or RT; pre-existing lung diseases (such as chronic obstructive pulmonary disease (COPD), respiratory failure and asthma); severe sleep apnea syndrome (apnea-hypopnea index >40); body mass index (BMI) >30 kg/m2; communication barrier; history of neuropsychiatric disorders, cerebrovascular diseases, abnormalities of renal or hepatic function; nasopharyngeal surgery; second- or third-degree atrioventricular block; bradycardia (heart rate (HR) <60 beats per minute); drugs or alcohol abuse; participating in other clinical trials nearly 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the successful completion rate of procedure; | — |
Secondary
| Measure | Time frame |
|---|---|
| time metrics, hemodynamics;intubating conditions, lowest oxygen saturation, severity of coughing,;number of remedies, total dose of fentanyl, RF, RT and Dex, incidence of dreaming,;patient and bronchoscopist satisfactions, willingness to the repeat bronchoscopy; | — |
Countries
China
Contacts
Public ContactQing Lv
Liaocheng People's Hospital
Outcome results
None listed