Acute repiratory failure
Conditions
Interventions
Group of HFNC:Treated with HFNC
Group of intubation:Mechanical ventilation under intubation
Sponsors
Children's Hospital of Nanjing Medical University
Eligibility
Sex/Gender
All
Age
0.1 Years to 14 Years
Inclusion criteria
Inclusion criteria: 1. Patients who choose to be admitted to the ICU, 28 days =7.3).
Exclusion criteria
Exclusion criteria: 1. Patients who died within 24 hours after being admitted to the ICU; 2. Severe type I respiratory failure, P/F<100mmHg; 3. Children who need immediate tracheal intubation due to suffocation, poisoning, shock, severe nervous system injury, etc., who cannot perform procedural intubation; 4. Children selected for intubation due to diagnostic or therapeutic procedures (bronchoscopy, surgery); 5. Received non-invasive ventilation when HFNC was intolerant; 6. Those with severe nasal obstruction or those who cannot wear HFNC for facial or upper airway surgery; 7. Poor airway protection and high risk of aspiration; 8. Metabolic diseases, autoimmune diseases, immunodeficiency diseases, tumors, and those who have recently received immunosuppressive therapy; 9. Cases with special diseases such as partial organ transplantation, bone marrow dysplasia, human immunodeficiency virus (HIV) infection; 10. Patients with incomplete clinical data, and those whose family members are unwilling to accept the trial in the clinical trial and request to withdraw.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rate of HFNC successful treatment;Survival rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Arterial blood gas analysis;Liver and kidney function; | — |
Countries
China
Contacts
Public ContactMiao Hongjun
Children's Hospital of Nanjing Medical University
Outcome results
None listed