Time-varying characteristics and influencing factors of cognitive function in elderly patients with depression and mild cognitive impairment

A cohort study of cognitive function in elderly patients with depression with mild cognitive impairment

Status

Active, not recruiting

Phases

Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2200058667

Enrollment

Unknown

Registered

2022-04-13

Start date

2022-04-20

Completion date

Unknown

Last updated

2024-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Late-life depression and mild cognitive impairment

Interventions

Case series:No

Eligibility

Sex/Gender

All

Age

60 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1. The age of the patients is >=60 years old, and the diagnosis and treatment information is complete; 2. The diagnostic criteria for depression and MCI are met at the same time; 3. The patients are willing to participate in this study and have basic comprehension and verbal expression skills.

Exclusion criteria

Exclusion criteria: 1. Relevant past history affecting cognitive function: various types of stroke, traumatic brain injury, severe brain atrophy, mental disorders; 2. Perennial alcohol addiction, or long-term use of various drugs affecting mental state (sedatives, analgesics, etc.); 3. Malignant tumor , Survival period with tumor; 4. Patients with language, vision and hearing impairments, who are prone to errors in the process of quantifying cognitive function.

Design outcomes

Primary

Measure	Time frame
Montreal cognitive assessment;24 items Hamilton depression scale;	—

Secondary

Measure	Time frame
Short form 36 questionnaire;	—

Countries

China

Contacts

Public ContactRong Lin

linrong2015@126.com+86 0591-88217919

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026