Membranous nephropathy
Conditions
Interventions
Control group:Other treatment
Sponsors
People’s Hospital of Songzi
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Membranous nephropathy proven by renal biopsy; 2. Nephrotic syndrome, defined as the presence of nephrotic-range proteinuria > 3.5 g/d, serum albumin 60 ml/min per 1.73 m2; 4. No immunosuppressive agents used in the previous 6 months; 5. Follow-up time of at least 24 months; 6. Agree to accept the random assignment, understand and be willing to sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Serious complications such as thrombosis, renal failure and infection; 2. Serious diseases such as HIV, cardiac dysfunction, hepatitis B, hepatitis C or serum amino-transferase exceeding twofold the normal upper limit; 3. Other contraindications to immunosuppressants; 4. Hypersensitivity to macrolide medication; 5. Diabetes mellitus or the coexistence of other severe kidney diseases; 6. Pregnancy or lactation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Complete remission;Partial response; | — |
Secondary
| Measure | Time frame |
|---|---|
| Renal survival; | — |
Countries
China
Contacts
Public ContactZhou Yuan
People’s Hospital of Songzi
Outcome results
None listed