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Early predictive value of presepsin (soluble CD14 subtype) for sepsis secondary to severe acute pancreatitis in intensive care unit patients

Predictive Value of presepsin on structure and translocation of intestinal microbiota in patients with severe acute pancreatitis

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200058603
Enrollment
Unknown
Registered
2022-04-12
Start date
2022-04-01
Completion date
Unknown
Last updated
2024-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Severe acute pancreatitis

Interventions

Case series:No

Sponsors

the First Affiliated Hospital of Chongqing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.Meet the diagnostic criteria of severe acute pancreatitis (according to Classification of acute pancreatitis-2012: revision of the Atlanta classification and definitions by international consensus); 2.Aged 18-80 years old; 3.Time from onset of the disease to hospital admission of less than 72 hours.

Exclusion criteria

Exclusion criteria: 1. There are acute and chronic infectious diseases before and at the onset; 2. Serious chronic organ failure such as heart, liver, lung, kidney and blood system has existed before the onset; 3. Untreated malignant tumor; 4. Autoimmune disease or immunosuppression (solid organ or bone marrow transplantation, AIDS, long-term use of immunosuppressants or hormones, etc.); 5. Clinical data and residual blood samples are missing.

Design outcomes

Primary

MeasureTime frame
presepsin;—

Secondary

MeasureTime frame
PCT;CRP;IL-6;—

Countries

China

Contacts

Public ContactLuo Na

the First Affiliated Hospital of Chongqing Medical University

nana1229@126.com+86 23 89011768

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026