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The application of MRD dynamic monitoring in the efficacy evaluation of TACE combined with targeted immunotherapy for liver cancer

The application of MRD dynamic monitoring in the efficacy evaluation of TACE combined with targeted immunotherapy for liver cancer

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200058596
Enrollment
Unknown
Registered
2022-04-12
Start date
2022-05-01
Completion date
Unknown
Last updated
2024-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Liver Cancer

Interventions

Experimental group:TACE in combination with targeted immunotherapy

Sponsors

The Fifth Medical Center of PLA General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 110 Years

Inclusion criteria

Inclusion criteria: 1. Aged >=18 years; 2. No gender limit; 3. Patients with liver cancer confirmed by pathology; 4. Liver cancer patients receiving TACE combined with targeted immunotherapy; 5. Subjects voluntarily participate in the study and sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Insufficient tissue samples can be obtained for NGS detection; 2. Contraindications for TACE treatment; 3. Clinical information needed for research cannot be obtained; 4. Failure to cooperate with or agree to follow-up visits.

Design outcomes

Primary

MeasureTime frame
Tumor progression;

Secondary

MeasureTime frame
Minimal residual lesion (MRD) positive;

Countries

China

Contacts

Public ContactXie Hui
xh302r@126.com+86 13391507655

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026