Overactive Bladder
Conditions
Interventions
Experimental group:Mirabegron and behavior intervention
Control group:Mirabegron
Sponsors
Peking Union Medical College Hospital
Eligibility
Sex/Gender
All
Age
40 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Aged 40-60 years, general examination, nervous system examination and pelvic examination showed no abnormality; 2. Patients with symptoms of urgent urination for more than 3 months, with or without urge incontinence, often combined with frequent urination and nocturia, had normal urine routine; 3. For patients diagnosed with OAB through the following questionnaire, scores of 6=12 were considered severe 0AB, and moderate to severe OAB patients were selected into the group; 4. Volunteer and sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Other diseases with OAB symptoms; 2. Patients with hypertension, whose blood pressure is up to 180/110 mm Hg or above; 3. Gynecological malignancies, patients after pelvic radiotherapy, patients with stress urinary incontinence and patients with mixed urinary incontinence mainly stress urinary incontinence; 4. Patients taking OAB treatment drugs; 5. Pregnant patients (blood G-HCG must be determined when necessary) or lactating patients; 6. Patients with liver and kidney dysfunction, immunosuppressant treatment, blood diseases, diabetes, mental illness or suffering from other serious diseases; 7. Poor compliance; 8. Allergies or allergies to study medications.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Voiding diary;Overactive bladder symptom scale (OABSS);Overactive bladder syndrome questionnaire OAB-Q;Blood pressure;Frequency of urgent urination /24 hours;Urgent incontinence times /24 hours;Frequency of urination /24 hours;The number of nocturnal urination and the maximum urine output; | — |
Countries
China
Contacts
Public ContactShi Honghui
Outcome results
None listed