Second degree burn
Conditions
Interventions
Experimental group:Dewetai new hydrogel foam dressing
Control group:Conservative dressing change therapy
Sponsors
The First Affiliated Hospital of PLA Navy Military Medical University
Eligibility
Sex/Gender
All
Age
1 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Aged from 1 to 60 years (including boundary value), no gender limitation; 2. Patients admitted to hospital within 24 hours after injury were clinically diagnosed as second-degree burns and burn depth based on the four-degree and five-point method. For wound area estimation, Chinese nine-point method and palm method were used; 3. The total area of burn and scald is no more than 15%TBSA (total body surface area), and the subject area is 10-80cm^2, located in the limbs or trunk, with clean wound surface and no infection; Isolated wound surface was selected as the test area as far as possible; 4. The cause of burn is thermal burn; Including hot liquid (water, soup, oil, etc.), steam, high temperature gas, flame, hot metal liquid or solid (such as molten steel, steel ingot), etc.; 5. The subject is fully informed and the informed consent is signed voluntarily or by the guardian.
Exclusion criteria
Exclusion criteria: 1. Those who have contraindications or allergies to the study drugs or their ingredients; 2. Patients with clear and severe organ dysfunction, such as heart, brain, liver and kidney; 3. Severe wound contamination or infection of patients; 4. Immune dysfunction, HIV infected patients, or patients who have received radiation, hormone (systemic drug), chemotherapy, growth factors, or immunosuppressive drugs within 1 month; 5. Burns due to chemical, electrical, radiation and other special reasons; 6. Critically ill patients with inhalation injury, trauma and other multiple injuries; 7. Unstable blood glucose control, such as fasting blood glucose >=8.0mmol/L or postprandial blood glucose >=12.0mmol/L; 8. Those who suffer from mental disorders and have no self-awareness and cannot express themselves accurately; 9. Maternal or other investigator assessments are not appropriate for participating investigators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mean healing time; | — |
Secondary
| Measure | Time frame |
|---|---|
| Rate of wound deepening;Total wound healing rate;Wound pain assessment;Wound inflammation assessment;Evaluation of scar hyperplasia; | — |
Countries
China
Contacts
Public ContactXia Zhaofan
Outcome results
None listed