Preterm birth
Conditions
Interventions
experimental group:transvaginal two stiches cervical cerclage
control group:transvaginal one stich cervical cerclage
Sponsors
Maternal and Child Health Hospital of Fujian Province
Eligibility
Sex/Gender
Female
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1. Pregnant patients who received regular birth examination in Fujian Maternal and Child Health Hospital and delivered in our hospital; 2. Single pregnancy; 3. Sign informed consent; 4. Patients with a history of unexplained abortion and premature delivery during pregnancy; 5. Cervical insufficiency confirmed by cervical examination before pregnancy; 6. During the physical examination during pregnancy, painless dilation of the cervix and protrusion of fetal sac at the external cervix were found; 7. In the second trimester, ultrasound found that the length of the cervix was shortened and the inner cervix was dilated; 8. Good follow-up compliance.
Exclusion criteria
Exclusion criteria: 1. Iatrogenic preterm birth factors; 2. Systemic and reproductive tract infections; 3. Fetal chromosome abnormalities or congenital malformations; 4. Fetal growth restriction; 5. Genital tract malformation; 6. Abnormal placenta position; 7. Pregnancy complications: hypertensive diseases during pregnancy, ICP, stillbirth, etc.; 8. Pregnancy complications: obesity, diabetes, hypertension, autoimmune diseases, embolism, digestive diseases, malignant tumors, etc.; History of gastrointestinal surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gestational age at delivery;Live birth rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cervical height after cerclage;Prolonged pregnancy period;Fetal weight;Neonatal morbidity;NICU admission rate; | — |
Countries
China
Contacts
Public ContactPan Mian
Fujian Maternal and Child Health Care Hospital Affiliated to Fujian Medical University
Outcome results
None listed