Effects of general anesthetics on cerebral blood flow autoregulation

Effects of propofol on cerebral blood flow autoregulation in adults

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2200058532

Enrollment

Unknown

Registered

2022-04-10

Start date

2022-05-01

Completion date

Unknown

Last updated

2024-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Group 1:General anesthesia with propofol

Group 2:General induction of sevoflurane

Eligibility

Sex/Gender

All

Age

20 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Patients undergoing general anesthesia and invasive arterial puncture; 2. ASA grading ?-?; 3. Aged 20-60 years and the gender is not limited; 4. The patient has fully understood the nature of the study, voluntarily participated in the experiment and signed the informed consent.

Exclusion criteria

Exclusion criteria: 1. Those who are known to be allergic to the drug ingredients in this study and allergic constitution; 2. Infected ulcer at puncture site; 3. Coronary heart disease;. Bronchial asthma; Severe hypertension; Heart and lung diseases and liver and kidney insufficiency; 4. Obesity (BMI>30); 5. History of neurological diseases; Drug addiction and alcoholism; 6. Patients who have participated in clinical trials of other drugs within the last 4 weeks; 7. Poor compliance and inability to complete the experiment according to the study plan; 8. For any reason, the researcher considers that there are any circumstances unsuitable for inclusion.

Design outcomes

Primary

Measure	Time frame
Mean arterial pressure;Cerebral oxygen saturation;	—

Countries

China

Contacts

Public ContactShi Zhao

Tianjin Institute of Anesthesiology

541601582@qq.com+86 13652021211

Outcome results