cervical cancer
Conditions
Interventions
Group 1:adjuvant chemotherapy
Group 2:none
Sponsors
The Fourth Affiliated Hospital of Guangxi Medical University
Eligibility
Sex/Gender
Female
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Cervical squamous cell carcinoma, adenocarcinoma and adeno-squamous cell carcinoma confirmed by histopathology. 2. Patients with FIGO 2018 stage IB3,IIA2, IB-IVA. 3. Patients diagnosed with initial treatment of locally advanced cervical cancer received standard concurrent intensity modulated chemoradiotherapy and sequential three-dimensional postloading treatment, and the evaluated curative effect after treatment was CR. 4. Aged 18-75 years. 5. PS score 0-1. 6. Serum hemoglobin >=10 mg/dL, platelet >=100000/µL, neutrophil absolute count >=1500/µL. 7. Serum creatinine =60 ml/ min. 8. Serum bilirubin 6 months.
Exclusion criteria
Exclusion criteria: 1. Patients who have received neoadjuvant chemotherapy and surgery. 2. Patients with cognitive dysfunction. 3. Patients with any distant metastasis. 4. Patients with any other malignant tumor within 5 years. 5. Any other disease or condition that is contraindicated for chemoradiotherapy (e.g. active infection, 6 months after myocardial infarction, symptomatic heart disease, including unstable angina, congestive heart failure, or uncontrolled arrhythmia, immunosuppressive therapy). 6. Pregnant and lactating patients, or female patients who are fertile but have not taken contraceptive measures. 7. Patients with severe bone marrow dysfunction. 8. Patients with bleeding tendencies. 9. Drug or alcohol addicts. 10. Patients known to have a degree 3 or 4 allergic reaction to any of the treatments in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Overall Survival;Progress Free Survival; | — |
Countries
China
Contacts
Public ContactFeng Chengjun
The Fourth Affiliated Hospital of Guangxi Medical University
Outcome results
None listed