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Study on the mechanism of cancer pain treated with Ailitong ointment based on NGS gene polymorphism

Study on the mechanism of cancer pain treated with Ailitong ointment based on NGS gene polymorphism

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200058515
Enrollment
Unknown
Registered
2022-04-10
Start date
2022-04-01
Completion date
Unknown
Last updated
2024-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cancer Pain

Interventions

Control group:Oral Oxycontin
Treatment group:Oral Oxycontin and external Ailitong ointment

Sponsors

Foshan Hospital of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients with tumors confirmed by pathology or cytology; 2. Patients with moderate to severe cancer pain assessed by NRS; 3. No intellectual or mental disorders, normal language expression ability, ability to judge their own pain and general conditions, and can cooperate to evaluate pain and quality of life content; 4. No analgesics or sedatives were used within 4 hours before enrollment, and no sustained-release analgesics were used within 12 hours; 5. The expected survival is at least 3 months; 6. No serious disorders in blood routine, heart, liver and kidney function; 7. The coagulation function is basically normal; 8. Aged 18 and 80 years.

Exclusion criteria

Exclusion criteria: 1. Patients allergic to Ailitong and Oxycontin; 2. Pregnant and lactating patients; 3. Radiotherapy and chemotherapy affect patients; 4. Treatment is not the author; 5. Patients who are too weak to tolerate cancer pain treatment.

Design outcomes

Primary

MeasureTime frame
Genes of primary tumor;Gene CYP2D6;Endogenous cannabinoid AEA and 2-AG;Specific cannabinoid receptors CB1 and CB2;

Countries

China

Contacts

Public ContactChen Xuezhang

Foshan Hospital of Traditional Chinese Medicine

48183002@qq.com+86 13923111432

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026