stroke
Conditions
Interventions
intervention group:Tirofiban was used after intravenous thrombolysis
control group:Routine treatment after intravenous thrombolysis
Sponsors
Kunshan First People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria for acute ischemic stroke; 2. Acute stroke patients with hyperactivity and intravenous thrombolysis time window (contraindications refer to the Scientific Statement of the Chinese Stroke Society for Intravenous Thrombolysis of Acute Ischemic Stroke and the Chinese Guidelines for Early Endovascular Intervention for Acute Ischemic Stroke 2018); 3. Sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Accompanied by seizures; 2. Present or past 6 months of significant hemorrhagic disease; 3. History of severe central nervous system damage (e.g. tumor, aneurysm, arteriovenous malformation, intracranial or spinal cord surgery); 4. Patients with mental disorders, including schizophrenia or other mental illnesses; 5. Patients with severe liver and kidney insufficiency; 6. Patients who are allergic to tirofiban hydrochloride and have thrombocytopenia or agattriban after previous use of tirofiban hydrochloride are not suitable for anti-platelet aggregation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Aggravation of neurological symptoms; | — |
Secondary
| Measure | Time frame |
|---|---|
| Intracerebral hemorrhage transformation; | — |
Countries
China
Contacts
Public ContactZhang Yan
Kunshan First People's Hospital
Outcome results
None listed