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Based on RhoA/ROCK signaling pathway, the mechanism of Xiaoshuan Changrong capsule on cerebral infarction convalescence was studied

Based on RhoA/ROCK signaling pathway, the mechanism of Xiaoshuan Changrong capsule on cerebral infarction convalescence was studied

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200058501
Enrollment
Unknown
Registered
2022-04-10
Start date
2022-04-01
Completion date
Unknown
Last updated
2024-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

stroke

Interventions

Western medicine and Xiaoshuan Changrong capsule group:Western medicine and Xiaoshuan Changrong capsule
Western medicine group :Western medicine
Healthy control group:None

Sponsors

Shanxi University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
35 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Patients who meet the diagnosis of acute cerebral infarction and are confirmed by CT or MRI; 2. NIHSS score: 4-15 (including 4 and 15 points); 3. Patients aged between 35 and 75 years; 4. Onset time within 7 days; 5. Patients with stable vital signs, clear consciousness and no serious complications; 6. Patients with first onset or previous history of stroke without limb paralysis and other sequelae; 7. Good compliance with this study; 8. Patients or family members sign informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with stroke caused by cerebrovascular inflammatory reaction; 2. Patients with stroke caused by cardiogenic factors such as atrial fibrillation; 3. Patients with acute cerebral infarction or repeated cerebral infarction; 4. Hemorrhagic disease; 5. Pregnant and lactating patients; 6. Patients with hearing and other dysfunction who cannot cooperate with the assessment; 7. Participated in other clinical trials within the last 90 days.

Design outcomes

Primary

MeasureTime frame
Serum levels of Nogo-A and NgR1;RhoA and ROCK levels in serum;

Countries

China

Contacts

Public ContactHu Fengyun
Fengyun71@163.com+86 13834233638

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026