Chronic kidney disease
Conditions
Interventions
Experimental group:Conventional treatment combined with Shenkang suppository
Control group:Conventional therapy
Sponsors
Affiliated Hospital of Xuzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: CKD1-4 non dialysis patients aged 18-70 years in the Department of Nephrology, Affiliated Hospital of Xuzhou Medical University.
Exclusion criteria
Exclusion criteria: 1. Use antibiotics, probiotics, prebiotics and other drugs to remove urinary toxins within 4 weeks; 2. Active inflammatory diseases in the last 2 weeks; 3. Complex and serious liver diseases, malignant tumors, active pulmonary tuberculosis, blood diseases, hyperthyroidism, adrenal diseases, etc.; 4. The experimenter does not meet the standard or does not accept it.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intestinal flora ((Increase in beneficial bacteria and decrease in pathogenic bacteria));Intestinal derived uremic toxins (Indoxyl Sulfate, IS; p-Cresol Sulfate, PCS; Trimethylamine Oxide, TMAO); | — |
Secondary
| Measure | Time frame |
|---|---|
| Renal function indicators (creatinine, glomerular filtration rate (eGFR), etc.); | — |
Countries
China
Contacts
Public ContactSun Dong
Affiliated Hospital of Xuzhou Medical University
Outcome results
None listed