spine surgery postoperative chronic pain
Conditions
Interventions
Group 1:Intraoperative maintenance of moderate muscle relaxation (TOF: 1-3)
Group 2:Intraoperative maintenance of deep muscle relaxation (PTC: 1-2)
Sponsors
The Affiliated Hospital of Xuzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Age 18-65 years; 2. Patients undergoing elective spinal surgery under general anesthesia; 3. ASA classification I-III.
Exclusion criteria
Exclusion criteria: 1. Preoperative chronic pain or hyperalgesia; 2. Known allergy to cisatracurium or neostigmine; 3. Unable to communicate normally: hearing impairment, language comprehension impairment, mental illness, etc.; 4. History of spine surgery; 5. BMI >= 35 kg/m2; 6. Cancer patients; 7. Chronic infection patients; 8. Presence of neuromuscular disorders that may interfere with data collection; 9. Peripheral neuropathy caused by diabetes; 10. Long-term use of analgesics; 11. History of alcohol or drug abuse.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative chronic pain incidence; | — |
Secondary
| Measure | Time frame |
|---|---|
| Visual analogue scale score in PACU, 2h, 4h, 12h, 24h, 48h after operation;15-item quality of recovery scale score on the second day after surgery, before discharge, and 3 months after surgery;Intraoperative muscle relaxant dosage;Dosage of propofol, sevoflurane, remifentanil;extubation time;Postanesthesia care unit (PACU) stay time;The incidence of hypoxemia;Postoperative analgesic dosage;Readmission/admission rate for pain; | — |
Countries
China
Contacts
Public ContactSu Liu
The Affiliated Hospital of Xuzhou Medical University
Outcome results
None listed