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Long-term observational study of chronic hepatitis B-related cirrhotic nodules

Long-term observational study of chronic hepatitis B-related cirrhotic nodules

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200058435
Enrollment
Unknown
Registered
2022-04-09
Start date
2022-07-01
Completion date
Unknown
Last updated
2024-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hepatitis B cirrhosis

Interventions

Regenerative nodule:Carry out B-ultrasound, CT, MRI and laboratory examination, etc.
Low-grade dysplastic nodules (LGDN:Carry out B-ultrasound, CT, MRI and laboratory examination, etc.
High-grade dysplastic nodules (HGDN):Carry out B-ultrasound, CT, MRI and laboratory examination, etc.

Sponsors

The Third Hosptial of Zhenjiang Affiliated Jiangsu University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 99 Years

Inclusion criteria

Inclusion criteria: All patients with liver cirrhosis treated in the third people's Hospital of Zhenjiang City from February 2022 to February 2027 1. No age limit, no sex limit; 2. Meet the diagnostic criteria of hepatitis B infection (records show that HBsAg is positive for more than 6 months, or confirmed by liver biopsy); 3. The diagnosis of liver cirrhosis conforms to the diagnostic criteria of the guidelines for the Prevention and treatment of chronic Hepatitis B (2019 Edition) of the Hepatology Branch of the Chinese Medical Association and the infection Branch of Chinese Medical Association; 4. Patients with liver nodules found by ultrasound, CT, and MRI.

Exclusion criteria

Exclusion criteria: 1. Dropout and missing patients; 2. Patients with mental disorders complicated with other major diseases; 3. Patients clinically diagnosed as liver cancer; 4. Liver cirrhosis patients with other liver diseases such as other viral hepatitis, autoimmune liver disease, drug-induced liver disease, etc.

Design outcomes

Primary

MeasureTime frame
Alpha fetoprotein;AEP-L3;Des-gamma-carboxy prothrombin;ALT;Blood routine;Blood glucose measurement;AST;Abdominal ultrasound: including blood flow velocity, blood flow, diameter of hepatic artery, etc.;Density, size, shape and quantity of plain scan and enhanced display in CT;MRI: arterial blood supply, T1WI, T2WI;Pathological results of liver biopsy;

Countries

China

Contacts

Public ContactTan Youwen

The Third Hosptial of Zhenjiang Affiliated Jiangsu University

tyw915@sina.com+86 13914567088

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026