Digestive tract disease
Conditions
Interventions
TRD Group:Dextromex was replaced with an equivalent dose of propofol
TRP Group: Propofolwas replaced with dextromex an equivalent dose of
Sponsors
General Hospital of Northern Theater Command
Eligibility
Sex/Gender
All
Age
65 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1. Aged >65 years old; 2. ASA classification II~III; 3. BMI<30kg/m2; 4. Signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Excessive mental stress; 2. Severe cardiovascular, respiratory, neuropsychiatric and endocrine diseases; 3. A history of drug and alcohol dependence; 4. Difficult airway; 5. Patients with severe liver and kidney dysfunction, acute upper gastrointestinal bleeding with shock, severe anemia, mental illness, cognitive impairment, serious heart disease, coagulation disorder, nosebleed or other patients who cannot tolerate surgery; 6. Pneumothorax, COPD, abnormal upper respiratory tract (obstruction, severe stenosis); 7. Circulatory and respiratory diseases that may threaten life, such as uncontrolled severe hypertension, severe arrhythmia, unstable angina, acute respiratory infections, asthma attacks, etc.; 8. Other diseases causing hypoxia that could affect the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Oxygen saturation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Mean arterial pressure;Bispectral Index;Heart rate;Respiratory rate; | — |
Countries
China
Contacts
Public ContactSong Dandan
General Hospital of Northern Theater Command
Outcome results
None listed