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Surgical management and clinical outcomes of atrial functional atrioventricular regurgitation

Surgical management and clinical outcomes of atrial functional atrioventricular regurgitation

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200058402
Enrollment
Unknown
Registered
2022-04-08
Start date
2022-03-31
Completion date
Unknown
Last updated
2024-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atrial functional atrioventricular regurgitation

Interventions

None listed

Sponsors

Zhongshan Hospital affiliated to Fudan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. No less than 3+ AVR was detected by echocardiography, and the patient was therefore received operation; 2. More than 1 year history of long-standing AF; 3. Left ventricular ejection fraction(LVEF)>50%; 4. Left atrial diameter>40mm; 5. Normal Left ventricular end contractile diameter (23~35mm).

Exclusion criteria

Exclusion criteria: 1. Primary valvular lesions, such as Rheumatic or degenerative changes; 2. Severe CHD(meet PCI or CABG indications); 3. Preoperative echocardiography showed abnormal systolic activity of the ventricular wall; 4. History of other serious arrhythmias or other structural heart diseases; 5. Previous cardiovascular surgery (including interventions like pacemaker implantation, not including failed transcatheter ablation of AF); 6. Patients with severe liver or kidney dysfunction, or other serious diseases that may lead to poor prognosis, as determined by the investigator.

Design outcomes

Primary

MeasureTime frame
Survival condition;Severity of MR;Severity of MR;

Secondary

MeasureTime frame
Severity of TR;Size of mitral annulus;Left atrial diameter;Left Ventricular Ejection Fractions;Cardiac function;Severity of TR;Left atrial diameter;Left Ventricular Ejection Fractions;Cardiac function;

Countries

China

Contacts

Public ContactLi Jun

Zhongshan Hospital affiliated to Fudan University

li.jun@zs-hospital.sh.cn+86 13774240314

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026