Cardiac hypertrophy & Heart failure
Conditions
Interventions
Stage A heart failure group:N/A
Stage B heart failure group:N/A
Stage C heart failure group:N/A
Sponsors
Guangzhou First People's Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Meet the clinical diagnostic criteria of myocardial hypertrophy, essential hypertension and heart failure; 2. Patients who have no hypertensive emergency, hypertensive crisis attack, acute coronary events and acute heart failure attack or hospitalization in the past 1 month; 3. The patients are informed and sign the informed consent voluntarily.
Exclusion criteria
Exclusion criteria: 1. Patients with secondary hypertension; 2. Clearly diagnose patients with coronary artery disease; 3. Clearly diagnose patients with myocarditis or cardiomyopathy, such as hypertrophic cardiomyopathy, dilated cardiomyopathy, restrictive cardiomyopathy, etc.; 4. Clearly diagnose patients with infective endocarditis and pericardial disease; 5. Patients with cardiac hypertrophy and heart failure caused by non-hypertensive factors such as severe valvular heart disease, diabetes, chronic kidney disease; 6. Patients with asthma, other allergic diseases and parasitic infections; 7. Patients with severe hepatic and renal insufficiency; 8. Patients with malignant tumors.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 24-hour ambulatory blood pressure;cardiac structure and function;NT-proBNP;Eosinophil counting;Level of ECP;Level of EDN; | — |
Secondary
| Measure | Time frame |
|---|---|
| Neutrophil counting;Level of connective tissue growth factor;Level of intercellular cell adhesion molecule-1;Level of vascular cell adhesion molecule-1;6-minute walk test; | — |
Countries
China
Contacts
Public ContactYang Chongzhe
Guangzhou First People's Hospital
Outcome results
None listed