esophageal lesion
Conditions
Interventions
Group 1:5% sodium thiosulfate solution
Group 2:2% vitamin C solution
Group 3:2% vitamin C + 1% sodium thiosulfate solution
Sponsors
The First Affiliated Hospital with Nanjing Medical University
Eligibility
Sex/Gender
All
Age
45 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Aged between 45 and 75 years, regardless of gender; 2. The patient needs to undergo ordinary gastroscopy; 3. Sign the informed consent form and agree to follow the test requirements.
Exclusion criteria
Exclusion criteria: 1. Pregnant or lactating patients; 2. Patients with other serious diseases, such as heart disease, severe liver and kidney diseases, malignant tumors, etc.; 3. Patients who have received chemoradiotherapy; 4. Patients with bleeding, perforation, pyloric obstruction, and discomfort events or potential risks associated with cancer; 5. Patients with mental disorders or severe neurosis; 6. Patients with gastroesophageal reflux disease, reflux esophagitis, Barrett's esophagus, esophageal cancer, esophageal varices or esophageal ulcers; 7. Patients with biopsy contraindications; 8. Allergy to iodine, vitamin C, sodium thiosulfate and sodium bicarbonate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mucosal irritation symptoms; | — |
Secondary
| Measure | Time frame |
|---|---|
| Iodine fading effect; | — |
Countries
China
Contacts
Public ContactZhang Guoxin
Outcome results
None listed