Acute Pancreatitis
Conditions
Interventions
Intervention group:neostigmine
Control group:normal saline
Sponsors
Peking Union Medical College Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Aged between 18 years (inclusive) and 75 years (inclusive); 2. Diagnosed with acute lipogenic pancreatitis or acute alcoholic pancreatitis; 3. See a doctor within 24 hours of the onset of illness; 4. Evidence of organ failure.
Exclusion criteria
Exclusion criteria: 1. Neostigmine allergy; 2. There is a taboo of ShinZ muscle injection: (1) Epilepsy; (2) Angina pectoris, arrhythmia, ventricular tachycardia, sinus bradycardia; (3) Mechanical intestinal obstruction, urinary obstruction, asthma; (4) Uncontrolled hypotension and elevated vagal tone; 3. Pregnancy; 4. Uncontrolled hypertension or other cardiovascular and cerebrovascular diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| voluntary defecation recovery time; | — |
Secondary
| Measure | Time frame |
|---|---|
| borborygmus;intra-abdominal pressure;intra-abdominal infection;hospital stay; | — |
Countries
China
Contacts
Public ContactZhu Huadong
Peking Union Medical College Hospital
Outcome results
None listed