Prostate cancer
Conditions
Interventions
Group P:individualized PEEP
Group C:traditional low level PEEP
Sponsors
The Second Affiliated Hospital of Anhui Medical University
Eligibility
Sex/Gender
Male
Age
65 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Pathological or cytological diagnosis of prostate cancer, laparoscopic radical resection of prostate cancer is proposed; 2. Aged >=65 years; BMI 18.5 ~ 25 kg/m^2; ASA grade ? or ?; 3. No obvious abnormality in lung function, no spinal cord or thoracic deformity, no difficult airway, asthma or COPD; 4. Estimated operation time >=2h; 5. Volunteers and sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Preoperative hypertension was not controlled or poorly controlled (SBP>=180mmHg or DBP>=110mmHg); 2. Severe respiratory complications (including but not limited to COPD, bullae, bronchiectasis, asthma, severe sleep apnea syndrome, pulmonary interstitial fibrosis, pulmonary heart disease, recent respiratory failure, etc.); 3. Severe damage of liver and kidney function; Severe cardiovascular diseases: such as severe coronary atherosclerosis, heart failure, myocardial infarction and other underlying diseases; 4. Participated in other clinical studies within the last 3 months; 5. Situations that other researchers consider inappropriate to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Perioperative lung function;Postoperative pulmonary complications; | — |
Secondary
| Measure | Time frame |
|---|---|
| Intraoperative respiratory mechanics; | — |
Countries
China
Contacts
Public ContactLi Yun
Outcome results
None listed