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A national, multi-center real world study of camrelizumab-based therapy in patients with metastatic NSCLC after failed first-line treatment with camrelizumab plus chemotherapy

A national, multi-center real world study of camrelizumab-based therapy in patients with metastatic NSCLC after failed first-line treatment with camrelizumab plus chemotherapy

Status
Active, not recruiting
Phases
Phase 4
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200058209
Enrollment
Unknown
Registered
2022-04-02
Start date
2022-04-01
Completion date
Unknown
Last updated
2023-12-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung Cancer

Interventions

Group 1 :
Group 2:
Group 3:

Sponsors

Sichuan Cancer Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Subjects sign written informed consent and voluntarily participate in this study; 2. Subjects diagnosed as non-small cell lung cancer (NSCLC) by histology or cytology; 3. Negative EGFR mutation and ALK fusion gene status tested by histology or plasma; 4. At least 18 years of age; 5. Subjects have previously received first-line camrelizumab and platinum-containing chemotherapy; 6. According to the judgment of the investigator, subjects who can receive camrelizumab-based therapy.

Exclusion criteria

Exclusion criteria: 1. Subjects who are receiving other immune drugs or immunotherapy; 2. Subjects who are participating in other clinical studies; 3. Subjects with other malignancies; 4. During period of pregnancy or breastfeeding; 5. Not suitable for participation in the opinion of investigators.

Design outcomes

Primary

MeasureTime frame
Overall survival time, OS;

Secondary

MeasureTime frame
Progression-free survival, PFS;Objective response rate, ORR;Disease control rate, DCR;Duration of remission;safety;

Countries

China

Contacts

Public ContactJin Zhou

Sichuan Cancer Hospital

zhoujt521@163.com+86 17708177615

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026