The role of androgen receptor in the early diagnosis of effective hormonal treatment in children with severe hypospadias

The role of androgen receptor for hormonal treatment in children with severe hypospadias and the study of gene mechanism

Status

Active, not recruiting

Phases

Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2200058167

Enrollment

Unknown

Registered

2022-03-31

Start date

2022-04-01

Completion date

Unknown

Last updated

2023-12-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypospadias

Interventions

None listed

Eligibility

Sex/Gender

Male

Age

1 Years to 6 Years

Inclusion criteria

Inclusion criteria: 1. One to 6 years old boy, with severe hypospadias, and associated with chordee and penile hypoplasia.

Exclusion criteria

Exclusion criteria: 1. Primary gonadal hypoplasia, DSD, 5a-reductase deficiency, or other external genitalia anomalies.

Design outcomes

Primary

Measure	Time frame
Androgen receptor expression;Glans width;	—

Secondary

Measure	Time frame
Dihydrotestosterone;	—

Countries

China

Contacts

Public ContactZhilin Yang

Shenzhen Children’s Hospital

yangzhilin207@163.com+86 18938690841

Outcome results