Inflammatory bowel disease, periodotitis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. The age is 30-65 years old, and the gender is unlimited. 2. According to the consensus opinion on the diagnosis and treatment of inflammatory bowel disease published in 2018. the patients wered diagnosed as IBD and at active stage. 3. According to the staging criteria of periodontitis in the new international classification of periodontal diseases and peri implant diseases in 2018, the patients were diagnosed as periodontitis and classified as stage III/?. 4. Patients who agree to participate in the clinical trial and sign the informed consent voluntarily.
Exclusion criteria
Exclusion criteria: 1. Patients who had history of periodontal treatment within six months; 2. Patients with a history of IBD surgery; 3. Pregnant or nursing women; 4. Patients with acute infection, cardiopulmonary dysfunction, hemorrhagic disease and malignant tumor; 5. Patients who had history of antibiotics in at least one month; 6. Other conditions considered inappropriate for inclusion by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement value of disease activity score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Effective rate;Simple endoscopic score, SES;Intestinal flora;Periodontitis examination indicators;Inflammation Marker; | — |
Countries
China
Contacts
Nanjing Stomatological Hospital, Medical School of Nanjing University