Hip fracture
Conditions
Interventions
Low BIS group:BIS 35-50
High BIS group:BIS 50-65
Sponsors
The First Affiliated Hospital of University of Science and Technology of China
Eligibility
Sex/Gender
All
Age
65 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1. Hip surgery patients aged >= 65 years; 2. Fried Frailty Screening Scale score of 3 or above, and Clinical Frailty Scale (CFS) grade 5 or above; 3. American Society of Anesthesiologists (ASA) classification II-IV; 4. The patients were tested voluntarily and signed the informed consent.
Exclusion criteria
Exclusion criteria: 1. Severe heart, lung, liver and kidney dysfunction; 2. History of mental illness or long-term psychotropic drugs (dementia, schizophrenia), history of chronic analgesic drug use, history of alcoholism; 3. Preoperative Mini-Mental State Examination Scale (MMSE) <21 points, diagnosed with moderate to severe cognitive impairment; 4. Any cerebrovascular accident, such as stroke, transient ischemic attack (TIA), etc., occurred within 3 months; 5. Patients with severe infections; 6. Preoperative PaO2<60mmHg or SpO2<90%; 7. Participated in another clinical study of drugs within the past 30 days; 8. Language communication barriers, unable to complete the cognitive function test; 9. Those who are allergic to test drugs or have contraindications to fascia iliaca block.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of POD within 3 days after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| 30-day postoperative mortality;Days alive out of hospital;Postoperative ICU transfer rate;Postoperative hospital stay;Postoperative quality of recovery; | — |
Countries
China
Contacts
Public ContactChunlin Xie
The First Affiliated Hospital of University of Science and Technology of China
Outcome results
None listed