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Clinical study of PEGDA-based hydrogel for nasal hemostasis

Clinical study of PEGDA-based hydrogel for nasal hemostasis

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200058156
Enrollment
Unknown
Registered
2022-03-31
Start date
2022-03-31
Completion date
Unknown
Last updated
2023-12-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nosebleeds

Interventions

Control group: expansion sponge packing group:Inflation sponge packing for patients with epistaxis
Experimental group: balloon intervention gel group:Balloon interventional gel covering for patients with epistaxis

Sponsors

Beijing Friendship Hospital Affiliated to Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
19 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Nasal mucosa oozing; bleeding and mucosal erosion at the front of the nasal cavity, most of which occur in the Lis area; oozing and bleeding are more obvious, and the oozing surface is large but the bleeding site is clear or generally clear; 2. Age 19-65 years old, gender is not limited; 3. No accidental trauma to the nose; 4. Approved by the Medical Ethics Committee, the patients signed the informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with severe arterial fluctuating bleeding, allergic constitution, and coagulation dysfunction are temporarily not suitable for this study; 2. Poor compliance; 3. Accompanied by mental illness or intellectual disability, unable to cooperate with treatment; 4. Bleeding caused by trauma, tumor, blood system diseases; 5. Those with other system diseases such as asthma, cardiovascular and cerebrovascular diseases; 6. Those who are participating in clinical trials of other drugs.

Design outcomes

Primary

MeasureTime frame
Clinical efficacy;One-time hemostatic cure rate;Stuff retention time in both groups;

Secondary

MeasureTime frame
Pain score;

Countries

China

Contacts

Public ContactLiu Ke

Beijing Friendship Hospital Affiliated to Capital Medical University

liuke@ccmu.edu.cn+86 13811488642

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026