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Clinical study of PEGDA-based hydrogel against allergic rhinitis

Clinical study of PEGDA-based hydrogel against allergic rhinitis

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200058155
Enrollment
Unknown
Registered
2022-03-31
Start date
2022-03-31
Completion date
Unknown
Last updated
2023-12-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Allergic rhinitis

Interventions

Control group:Give "isotonic physiological saline" nasal spray
Nasal spray group:Give mometasone furoate nasal spray nasal spray
Balloon Interventional Gel Drug Loading Group:Give balloon intervention P-G gel loaded (mometasone furoate nasal spray) to cover

Sponsors

Beijing Friendship Hospital Affiliated to Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
19 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Meet the AR diagnostic criteria; 2. Age 19-65 years old, gender is not limited; 3. Total nasal symptom score (TNSS) >= 4 points; 4. Patients participated voluntarily and signed the informed consent.

Exclusion criteria

Exclusion criteria: 1. Those who are breastfeeding or pregnant; 2. Those who have taken antihistamines or glucocorticoids recently; 3. Combined with severe deviation of nasal septum or nasal polyps; 4. Those who have a history of sinusitis or have sinusitis after examination; 5. Those who have allergic reactions after taking loratadine; 6. Those with other system diseases such as asthma, cardiovascular and cerebrovascular diseases; 7. Those who are participating in clinical trials of other drugs.

Design outcomes

Primary

MeasureTime frame
Total nasal symptom score (TNSS);Total non nasal symptoms score (TNNSS);Rhinoconjunctivitis Quality of Life Questionnaire;Efficacy assessment;

Countries

China

Contacts

Public ContactLiu Ke

Beijing Friendship Hospital Affiliated to Capital Medical University

liuke@ccmu.edu.cn+86 13811488642

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026