obesity and its related metabolic disorders
Conditions
Interventions
Intermittent fasting:
Intermittent fasting & Konjac oligosaccharide:
Control group:NO
Control group & Konjac oligosaccharide:
Sponsors
Northwest Minzu University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1.18-65 years (including the critical value), no gender limitation; 2.BMI 25 or greater; 3.One can understand the procedures and methods of this study, be willing to strictly abide by the clinical trial protocol to complete this trial, and voluntarily sign an informed consent.
Exclusion criteria
Exclusion criteria: 1. Have not used antibiotics, prebiotics and probiotics for at least one month; 2. Known or suspected allergic constitution; 3. Various secondary hypertension syndromes (including renal parenchymal, renal vascular hypertension, endocrine and sleep apnea syndrome, etc.); 4. No autoimmune diseases such as lupus erythematosus and rheumatoid arthritis; 5. Other chronic diseases except metabolic syndrome (cirrhosis, chronic nephritis and tumors in other parts); 6. Have received coronary stent implantation in the past (i.e., cardiac stent surgery); 7. Complicated with tumor or previous tumor history or other major diseases of digestive, respiratory, blood and other systems; 8. Those who are prone to alcoholism or drug abuse or addiction; 9. Persons with other serious nervous and mental system diseases who are unable to cooperate or unwilling to cooperate to complete the prescribed examination items, or who are accompanied with suicidal tendencies; 10. Pregnant or lactating women or those who have a recent birth plan; 11. It is accompanied with obvious oral diseases, such as caries, periodontal diseases, mucosal related diseases, etc; 12. Those who have participated in other clinical researches; 13. Other situations that the investigator considers inappropriate to participate in this test.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gut microbiota;Fecal metabolome;Serum metabolome;Oral microorganism;Urine metabolome; | — |
Secondary
| Measure | Time frame |
|---|---|
| Other blood parameters;Other urine parameters;Body composition; | — |
Countries
China
Contacts
Public ContactJunhong Su
Northwest Minzu University
Outcome results
None listed