FindTrial
Sign In

Effects of recombinant human brain natriuretic peptide on hepatic surgical field bleeding score and central venous pressure in patients undergoing laparoscopic partial hepatectomy: a randomized controlled trial

Effects of recombinant human brain natriuretic peptide on hepatic surgical field bleeding score and central venous pressure in patients undergoing laparoscopic partial hepatectomy: a randomized controlled trial

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200058135
Enrollment
Unknown
Registered
2022-03-30
Start date
2021-08-01
Completion date
Unknown
Last updated
2023-12-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Liver disease

Interventions

Brain natriuretic peptide group:Recombinant human brain natriuretic peptide group
Non-brain natriuretic peptide group:Normal saline

Sponsors

Jiangsu Province Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 79 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18–79 years; 2. American Society of Anesthesiologists grades I–III; 3. scheduled for elective laparoscopic partial hepatectomy.

Exclusion criteria

Exclusion criteria: 1. Child-Pugh grade C; 2. Renal insufficiency; 3. Severe heart disease; 4. Poor control of hypertension and diabetes; 5. Coagulation disorders; 6. A history of upper abdominal surgery; 7. Open conversion prior to surgery; 8. Palliative surgery; 9. Intraoperative critical events; 10. Patients who did not undergo the Pringle maneuver.

Design outcomes

Primary

MeasureTime frame
hepatic surgical field bleeding score;—

Secondary

MeasureTime frame
general demographics;arterial blood pressure;heart rate;liver and kidney function;duration of anesthesia;duration of operation;blood loss;urine output;infusion;arterial blood gas;lump volume;airway pressure;pneumoperitoneal pressure;central venous pressure;postoperative complications and outcomes;—

Countries

China

Contacts

Public ContactBo Gui

Jiangsu Province Hospital

guibosy@163.com+86 13675163272

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026