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A randomized controlled study on the effect of abandoning anti-spasmodic drugs after finger replantation on finger survival

A randomized controlled study on the effect of abandoning anti-spasmodic drugs after finger replantation on finger survival

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200058130
Enrollment
Unknown
Registered
2022-03-30
Start date
2022-05-01
Completion date
Unknown
Last updated
2023-12-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Single finger amputation

Interventions

experimental group:1ml saline q8h intramuscular injection for 7 days
Control group:1 ml papaverine hydrochloride injection ( 30 mg / mL ) intramuscularly for 7 days

Sponsors

Subei people's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Various types of single finger disconnection (including complete disconnection and incomplete disconnection); 2. Replantation was performed within 6 hours after amputation and successful during operation; 3. Adult patients, = 18 years.

Exclusion criteria

Exclusion criteria: 1. People with anxiety, depression and other mental diseases; 2. Most of the fingers are severed; 3. Spasm of proper digital artery during replantation; 4. The severed finger is polluted by toxic chemical reagents; 5. Perioperative use of vasodilator and antispasmodic drugs such as alprostadil.

Design outcomes

Primary

MeasureTime frame
Survival rate of severed finger;

Secondary

MeasureTime frame
The incidence of vascular crisis;

Countries

People's Republic of China

Contacts

Public ContactLiu Hongjun

Subei people's Hospital

luka9999@163.com+86 18051060680

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026