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Dose effect relationship of pump injection of deoxyepinephrine to prevent hypotension after spinal anesthesia in obese pregnant women

Dose effect relationship of pump injection of deoxyepinephrine to prevent hypotension after spinal anesthesia in obese pregnant women

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200058125
Enrollment
Unknown
Registered
2022-03-30
Start date
2022-03-28
Completion date
Unknown
Last updated
2023-12-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cesarean section

Interventions

0.375:phenylephrine
0.5:phenylephrine
0.625:phenylephrine
0.75:phenylephrine

Sponsors

Linping District Women and Children Care Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1. Single obese parturients (body mass index>30kg/m2) who were selected for cesarean section; 2. ASA Class II; 3. Gestational age = 37 weeks; 4. Height 150-170cm.

Exclusion criteria

Exclusion criteria: 1. Hypertension or pre eclampsia; 2. Premature rupture of membranes; 3. Previous or gestational diabetes; 4. Intrauterine growth restriction, placenta previa, macrosomia, and any contraindication of spinal cord or epidural anesthesia, such as local infection and or bleeding.

Design outcomes

Primary

MeasureTime frame
Effective in preventing hypotension;—

Secondary

MeasureTime frame
Incidence of hypertension;Sensory block level;Bradycardia;Umbilical artery pH;—

Countries

China

Contacts

Public ContactLi Xing

Linping District Women and Children Care Hospital

18758070622@126.com+86 18758070622

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 6, 2026