Skip to content

The mechanism of acupuncture as an adjunctive therapy for alcohol use disorder based on multimodal bioinformatics

The mechanism of acupuncture as an adjunctive therapy for alcohol use disorder based on multimodal bioinformatics

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200058120
Enrollment
Unknown
Registered
2022-03-30
Start date
2022-04-01
Completion date
Unknown
Last updated
2023-12-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

alcohol use disorder

Interventions

acupuncture group:acupuncture+usual treatment
sham acupuncture group:sham acupuncture+usual treatment
normal control group:none

Sponsors

South China Research Center for Acupuncture and Moxibustion, Guangzhou University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Conform to the alcohol use disorder diagnosis in the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-V) of the American Psychiatric Association; 2. Male patients; 3. Aged 18-70 years; 4. The proposed or ongoing management of alcohol partition system; 5. Understand the test and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Accompanied with serious nervous system or mental disease caused by other diseases except alcohol dependence (including brain tissue damage caused by brain trauma); 2. Excluding the use of other psychoactive substances other than alcohol, including traditional drugs and new psychoactive substances; Daily smoking>30 cigarettes; 3. Patients with severe heart, liver, spleen, lung or kidney diseases; 4. Persons with syphilis or AIDS; 5. Those with severe digestive system diseases and severe malnutrition; 6. Patients with serious primary diseases of hematopoietic system; 7. Patients with abnormal coagulation function; 8. Those with inflammation, scar or trauma at the operation site, or those with severe systemic infection; 9. Those who have cognitive dysfunction, cannot cooperate or are receiving other treatments that may affect the evaluation of the efficacy of this intervention; 10. He has received acupuncture treatment in the past six months.

Design outcomes

Primary

MeasureTime frame
Time required for alcohol withdrawal symptoms to subside;

Secondary

MeasureTime frame
Change of the alcohol withdrawal symptoms;Change of the withdrawal craving;Change of the cue-induced craving;Change of the alcohol urge;Change of depression;Change of anxiety;Improvement of the sense of fatigue;Improvement of the sleep quality;Change of the self-efficacy;Change of the quality of life;Change of the digestive system dysfunction;Relapse or not;Percentage of heavy drinking days;Percentage of days abstinent;Drinks per drinking day;Drinks per heavy drinking day;

Countries

China

Contacts

Public ContactChunzhi Tang

South China Research Center for Acupuncture and Moxibustion, Guangzhou University of Chinese Medicine

jordan664@gzucm.edu.cn+86 13710333215

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 10, 2026