Diabetic peripheral neuropathy
Conditions
Interventions
diabetic peripheral neuropathy:nothing
diabetes without peripheral neuropathy:nothing
Sponsors
Shenzhen Hospital of Southern Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.The selected patients need to sign informed consent. 2.The patients diagnose diabetes according to the 1999 WHO diagnostic criteria for type 2 diabetes mellitus. 3.All patients must be =18 years old.
Exclusion criteria
Exclusion criteria: 1.The other causes for neuropathy including spondylopathy like radiculopathy, spinal stenosis, spondylosis, and cerebral infarction, Guillain-Barre syndrome, severe vascular disease, infection, immune abnormalities, drug-induced nerve injury , nutritional deficiencies, congenital diseases, trauma, etc. 2.The other causes for abnormal glucose and lipid metabolism including hyperthyroidism, hypothyroidism, Cushing's syndrome, hypothalamic and pituitary lesions, long-term use of glucocorticoids ,etc. 3.Type 1 diabetes, gestational diabetes. 4.The acute complications of diabetes including diabetic ketoacidosis, hyperglycemic hyperosmolar nonketotic coma. 5.The patients with severe liver disease, heart disease, long-term use of antibiotic, acute or chronic infection . 6.The pregnant women and those who plans to become pregnant. 7.The patients with acute or chronic infectious diseases and cancer. 8.Subjects who can't sign informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Insulin-like growth factor 1;Nerve conduction velocity;Sympathetic skin response;F wave;Quantitative sensory testing; | — |
Countries
China
Contacts
Public ContactXu Lingling
Outcome results
None listed